Presentations and Publications

Long-Lasting Analgesia in Rodents by siRNA-Mediated Silencing of Nav1.7.

February 29, 2024

Long-Lasting Analgesia in Rodents by siRNA-Mediated Silencing of Nav 1.7

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Widespread and Durable Knockdown of HTT in Non-Human Primate Brain…

February 29, 2024

Widespread and Durable Knockdown of HTT in Non-Human Primate Brain by a Novel Oligonucleotide Modality

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Alterman JF, Godinho BMDC, Hassler MR, et al. A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system. Nat Biotechnol. 2019 Aug;37(8):884-894 . doi:10.1038/s41587-019-0205-0

August 13, 2019

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Hassler MR, Turanov AA, Alterman JF, et al. Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo. Nucleic Acids Res. 2018;46(5):2185–2196. doi:10.1093/nar/gky037

October 14, 2018

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